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Volume 25, Issue 3, Pages 597-612 (August 2005)


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Positioning of Glucocorticosteroids in Asthma and Allergic Rhinitis Guidelines (Versus Other Therapies)

Guy F. Joos, MD, PhDaCorresponding Author Informationemail address, Guy G. Brusselle, MD, PhDa, Helen Van Hoecke, MDb, Paul Van Cauwenberge, MD, PhDb, Jean Bousquet, MD, PhDc, Romain A. Pauwels, MD, PhD

Asthma and allergic rhinitis are both characterized by airway inflammation, and glucocorticosteroids form the cornerstone of their pharmacologic treatment. All patients with asthma should be prescribed rapid-acting inhaled β2-agonists as needed to use as rescue therapy in case of symptoms. As soon as patients experience symptoms at least once a week, controller medications should be started on a daily basis to achieve and maintain control of their asthma. Intranasal corticosteroids are given as first-line therapy for moderate to severe persistent rhinitis. Depending on the dominant symptom, H1-antihistamines, decongestants, or ipratropium can be added after re-evaluation.

a Department of Respiratory Diseases, Ghent University Hospital, De Pintelaan 185, B-9000 Ghent, Belgium

b Department of Oto-rhino-laryngology, Ghent University Hospital, De Pintelaan 185, B-9000 Ghent, Belgium

c Service des Maladies Respiratoires, Hopital Arnaud de Villeneuve, Montpellier, France

Corresponding Author InformationCorresponding author

 Deceased January 3, 2005.

PII: S0889-8561(05)00038-X

doi:10.1016/j.iac.2005.06.001


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