Gastrointestinal eosinophilia, a broad term for abnormal eosinophil accumulation in the gastrointestinal tract, involves many different disease identities. These diseases include primary eosinophil associated gastrointestinal diseases, gastrointestinal eosinophilia in hypereosinophilic syndrome, and all gastrointestinal eosinophilic states associated with known causes. Each of these diseases has its unique features but there is no absolute boundary between them. All three groups of gastrointestinal eosinophila are described in this article, although the focus is on primary gastrointestinal eosinophilia.
Division of Allergy and Immunology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, University of Cincinnati, College of Medicine, 3333 Burnet Avenue, Cincinnati, OH 45229-3039, USA
Corresponding author.
This work was supported by NIH grants AI 45898-09, NIH AI 070235-02 and T32 DK 07727-12, The Buckeye Foundation, Campaign Urging Research for Eosinophilic Diseases (CURED) Foundation, The Food Allergy Project, and The Food Allergy and Anaphylaxis Network (FAAN).
This article was adapted from: Rothenberg ME. Eosinophilic gastrointestinal disorders (EGID). J Allergy Clin Immunol 2004;113(1):11–28.
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